Scitech & ISPE are hosting an event discussing AMR

AMR and the Role of the Pharma Industry

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Antimicrobial Resistance (AMR) is becoming a growing health problem and is regarded by most countries as the highest priority to be addressed by health agencies. While research on developing new classes of anti-infectious medicines is ongoing, it is also vital to address and review the existing control measures for release of antibiotic agents to the environment.  This will enable lowering the potential risk of impact to ecological resources and reduce the evolution and selection of AMR in the environment.

As highlighted in a publication by AMR Industry Alliance (1), the key areas where antibiotics and pharmaceutical manufacturers need to focus are defined and the recommended discharge concentrations for common antibiotics are now proposed (2). Most often, once the sources of release and discharge limits are defined, the existing technologies for waste treatment will suffice to remove the antimicrobial agents from the effluent streams. There are speculations that an EU commission will introduce/stipulate legislative measures for effluent treatment systems and even extending GMP practice to cover environmental controls (3).

Scitech has worked on many projects to handle process effluents and waste streams for different sites in the UK. We have collaborated closely with our clients to characterise process effluents and wastes, perform risk assessments and propose the good practices for containment, safe discharge and treatments from small scale laboratories to larger production facilities. Our solutions were either installation and commissioning of a new system or debottlenecking and upgrading existing installations by improving the philosophy and control of those existing systems.

Contact Scitech today to speak to one of our specialists about your facilities process effluents and waste streams.

  1. https://www.amrindustryalliance.org/shared-goals/common-antibiotic-manufacturing-framework/
  2. https://www.amrindustryalliance.org/wp-content/uploads/2018/09/AMR_Industry_Alliance_List-of-Predicted-No-Effect-Concentrations-PNECs.pdf
  3. https://www.amrindustryalliance.org/mediaroom/pharmaceuticals-in-the-environment/
  4. https://accesstomedicinefoundation.org/media/uploads/downloads/5bc5edd8367eb_Antimicrobial-Resistance-Benchmark-2018.pdf 
  5. https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0221568